Agoraphobia is characterized by avoidance or sustained fear of situations from which escape might be difficult (or help unavailable) in the event of a panic attack or other incapacitating or embarrassing symptoms. This can mean fear of leaving the safety zone of one’s home, but it can also manifest in other ways.  Agoraphobia is often associated with panic disorder.  CBT, as described above, is considered the most effective treatment for agoraphobia.